People at Heap
Frans van Andel, MSc, MPH, PhD
Dutch nationality. Senior Partner of HEAP Research BV. Degrees in health economics (Universities of Groningen and Utrecht) and public health (Harvard, USA). PhD in pharmaceutical economics. More than 25 years of experience in market access issues involving pharmaceuticals and medical devices with work experience in the pharmaceutical industry, CRO's and WHO. In addition, investment and healthcare restructuring projects (especially rehabilitation facilities for handicapped persons) for the public and private sector in Central and Eastern Europe, Africa, Middle East and Asia. Assignments from the health insurance sector, medical technology and pharmaceutical industries as well as institutional agencies such as the European Union, the World Bank and the Netherlands' Government. Expert in market access issues involving pharmaceuticals and medical devices, project development sourcing, health financing and insurance and public/private mix. Fluent in Dutch, English, German. Conversant in French and Russian.
Adam Barak, MCIM
British nationality, Senior Partner of HEAP Research BV. Degrees in Sales and Marketing. Mr Barak has 15 years of international pricing and reimbursement practice in healthcare for both industry and in consultancy with extensive experience in establishing global pricing and reimbursement strategies for pharmaceutical, biotech and medical device and diagnostics companies and healthcare services. Work experience at GSK, Oxford GlycoSciences and several major consultancy firms (a.o UBC). In 2002 Adam established ABPPC Ltd to provide the healthcare industry with specialised support in developing pricing, funding and market access strategies, out of which grew the international network PharmaPrice International (PPi), www.pharmaprice.net which Adam still heads, with offices in 25 countries and which works closely with HEAP Research BV. For 10 years to date, Adam and his companies have provided global coverage supporting some 300 assignments in commercialisation, planning and implementation for drugs, diagnostics, medical devices and healthcare services. Adam has experience with a multitude of therapeutic areas, has authored a number of publications, regularly presents to international audiences on international pricing, funding and market access topics and offers P&R training. Fluent in English, conversant in French.
Nico Bruyniks, MD, MRCOG, MFFP
Dutch nationality. Senior Partner of HEAP Research BV. Medical doctor with specialization in Obstetrics and Gynaecology (Member of the Royal College of Obstetricians and Gynaecologists), sub-specialisation in Reproductive Health (Member of the Faculty of Family Planning and Reproductive Health). About 22 years of pharmaceutical industry experience in Medical Affairs (Medical Director for Europe), Clinical Development (as Head Global Clinical Development Osteoporosis and Hormone Replacement Therapy and Vice-President Development, both clinical and pre-clinical) and General Management. Worked in large, mid-size and small (biotech) pharma companies in EU, Russian Federation and former Soviet Republics, Japan and the US. Has developed new affiliates for pharmaceutical companies in Eastern Europa as Medical Director for Eastern Europe, Benelux and the Nordics as General Manager. In-depth knowledge of product development, registration, market access and life cycle management. Therapeutic area experience includes, amongst others, women.s health, urology, osteoporosis, cardiology, diabetes, oncology, psychiatry and dermatology. Has also held an honorary lecturer position in Reproductive Health at the Netherlands School of Public Health. Fluent in Dutch and English, conversant in German and French.
Agnieszka Buksowicz, MSc
Polish nationality, Senior Consultant HEAP Research BV pharmaceutical registration systems and market access Poland and Eastern Europe. Master studies (1987 . 1992) Foreign Trade, School of Trade, Warsaw, Master of Economy and CeRAM Certificate . Trained and certified Regulatory Affairs Manager by the Polish Drug Agency (2007). Worked for Bayer AG from 1992 to 1996. Nowadays senior manager and consultant for drug registration, food supplements, medical devices, pharmacoeconomics, pharmacovigilance and consultancy in Regulatory Affairs in Poland. Member of international network of drug regulatory experts in the European Union. Fluent in Polish, English and German, conversant in French.
Antonie Brouwer, PharmD, MPH
Dutch nationality, Senior Consultant of HEAP Research BV. Degrees in pharmacy (University of Amsterdam) and Public Health (Harvard, Boston), More than 30 years of experience in hospital, wholesale and retail pharmacy. Set up a regional wholesale company in the Netherlands as well as a clinic for the treatment of international patients. Involved in many international projects sponsored by the European Union and Netherlands Government in Eastern Europe and Africa on issues such as GMP production, drug information, registration, wholesaling and retailing and drug recovery systems. Expert in pharmacy distribution issues and the set up of private enterprises in the health care sector Fluent in English, German. Conversant French.
Grigor Ghazaryan, MSc, PhD
Armenian nationality, Senior Consultant of HEAP Research BV. Degree in Mechanical Engineering (Yerevan Polytechnic Institute). PhD, Management in Social and Economic Systems (Moscow State University). Trainer certificate, Financial Market & Investment Funds (C.N.A. Veneto, Italy). Diploma, Banking (Louvain International Management Centre / De Nationale Investeringsbank N.V., The Hague). Over 22 years of senior executive experience in business environment reform, private sector development, financial sector development, fund management. Held several managerial positions: Armenian Republican Innovation Centre; Armenian National Financial-Investment Corporation; Armenian Business Corporation; Enterprise Support Fund; Armenian Development Agency; Joint Finance Facility of Black Sea Trade & Development Bank and Izmirlian Foundation. Expert in designing, launching, and managing multi-faceted international projects (World Bank, UNDP, USAID, DEG, GTZ/GIZ, ITC, JETRO, JICA), coordination of team-work in multinational environment. Representative of Netherlands Senior Experts (PUM) programme in Armenia. Fluent in Armenian, Russian, English.
Werner Gielsdorf, MSc, PhD
German nationality. Senior Consultant for clinical development of pharmaceuticals and medical devices. Studied Biology and Chemistry at Bonn University and graduated as Diplom-Biologist. Completed PhD on psycho-stimulant drugs in humans. Work experience in the public (EC Commission Kiev, German Drug Institute) and private sector (BMS, Solvay) in clinical research and development of pharmaceuticals - all phases of development. Senior expert in Health Care and Life Sciences sector (pharmaceutical issues) for governmental bodies and public institutions and the industry. Consulting governmental bodies in the healthcare sector in Central- and Eastern Europe (public health, national drug policy, regulatory compliance issues, and effective administration). Extensive international project management experience in the chemical and pharmaceutical industry (R&D, Marketing, Business development), regulatory compliance issues, supporting national authorities in the health care sector to comply with EU and other regulation and drug development. Recently completed a comparative analysis of Russian and EU Good Clinical Practice Rules on behalf of the European Commission. Fluent in German and English, conversant in Russian.
Ron de Graaff, LLM
Dutch nationality, Senior Partner of HEAP Research BV. Ron has a degree in law from the Free University Amsterdam and has focussed his professional life on health insurance and health financing issues as well as dental care and medical device and pharmaceutical reimbursement. Ron is a senior expert in issues of DRG financing (or in Dutch DBC) in the Netherlands. Over the years he has advised more than 400 private and public sector health care providers, insurers and manufacturers of pharmaceuticals and medical devices giving advice mainly in the field of strategy and policy structures, related to and resulting form the finance structures of the Dutch healthcare system (over 1,500 projects). Mr de Graaff is also Managing Director of Seijgraaf BV (www.seijgraaf.nl) and the Chairman of the Netherlands Association of Dentists. His past duties involved: Chairman of Umbrella Organization of Medical Technology in the Netherlands (SOMT) and various advisory roles of the Dutch Healthcare Authority and the National Reimbursement Authority. Fluent in Dutch, English, German. Conversant in French and Spanish.
Katrien De Groote, Pharm, PhD.
Belgian nationality. Senior consultant and founder of INNOSENS bvba (www.innosens.be). Katrien holds a PhD. Degree in Pharmacy from the Catholic University of Leuven. During her 14-year career in the pharmaceutical industry she held different positions as Medical Advisor, Health Scientist for pharmaco-economic projects, Health Economics Manager Benelux, Medical Manager and Pricing, Reimbursement and Market Access Manager for the Benelux/Alpine (Austria/Switzerland) region. In these positions she was responsible for the initiation and conduct of clinical trials in Belgium (phase III to phase IV/phase V studies), pharmacovigilance, training of sales representatives, medical information, submitting pricing and reimbursement dossiers for drugs and medical devices, developing health economic dossiers and giving strategic support to the Marketing and Sales Department.
During this 14-year period, she built up an in-depth knowledge of pricing and reimbursement environment and market access opportunities within the European Union. She built up a strong network with Key Opinion Leaders in several diseases areas, Health Authorities and Payers within the Benelux.
She is passionate about personal and interpersonal development and innovation projects. Fluent in Dutch, English and French. Notions of German.
Bas Janssen MSc, PhD
Dutch nationality, Senior Consultant HEAP Research BV in phamacoeconomic modelling, psychometric and quality of life studies. Master degrees in clinical psychology and philosophy from the University of Amsterdam. Has completed a PhD on the methodology of Quality Adjusted Life years. Over 8 years of research experience in Patient Reported Outcomes (PROs), utility and health-related quality of life measurement, psychometrics and health economics. Has been an active member of the EuroQol Group since 2005 and is currently involved in several EuroQol funded projects as principal researcher. Has been principal investigator in the development of the EQ-5D-5L, and has extensive experience in the valuation of health outcomes, the development of condition specific preference based measures and mapping studies. Has been working as a consultant and senior researcher since 2008. Bas also works as a part time professional musician. Fluent in Dutch and English, conversant in German.
Harm Luth, RN, MA
Dutch nationality, Senior Consultant of HEAP Research BV. Certified trainer and expert in training groups. Mr. Luth is NLP-master and systemic therapist, and has been (therapeutically) working with organizations and individuals more than 15 years. Has more than 25 years of experience as a manager in psychiatric healthcare (community psychiatry). Nowadays he is involved in several healthcare-projects in Romania and Turkey. He worked as a therapist-trainer for Marezate-Baarn, and had a private practice for individual psychotherapy. Worked for a major psychiatric institution in the Netherlands. He specialized in business administration and informatics, and developed in 1990 a method for effective nursing in chronic psychiatry. Expert in combining -tailor-made and targeted- training in professional communication and group therapy. Fluent in Dutch, English, German, Romanian. Conversant in French.
Mayya Makhmudova, MD, PhD
Uzbek nationality. Senior Consultant of HEAP Research BV in quality management systems in health care in general and in the blood sector in particular. Maya has more than 15 years of experience in developing QA management systems in primary and secondary care in health systems of many different countries such as Tadjikistan, Uzbekistan, Kyrgyzstan and Kazakhstan. From 2005 to 2011 she served as Blood Safety Programme Manager of the Women and Child Health Development Project in Uzbekistan sponsored by the Asian Development Bank. During this period she directed blood service reform, developed and taught QA management systems in MCH focussing on peri-natal and post-natal services in general and blood procurement in particular. Dr Makhmudova is an internationally recognised expert in QA systems and transfusion medicine and serves as expert to WHO, GF, ADB and the World Bank. Fluent in Russian, English and Uzbek, conversant in German.
Cees Smit Sibinga, MD, PhD, FRCP Edin, FRCPath
Dutch nationality. Senior Partner HEAP Research BV and senior expert in reform of the blood procurement system. Degrees in medicine, clinical haematology (University of Groningen) and transfusion medicine (Royal College of Physicians of Edinburgh and Royal College of Pathologists, London, UK). PhD in Medicine (University of Groningen). More than 30 years of experience in blood safety projects involving organizational, legislative and quality management aspects of reforms of blood supply systems in Central and Eastern Europe, Africa, Middle East and Asia. Former Medical Director of the Regional Blood Bank Groningen (northern part of the Netherlands. Expert (professor at the University of Groningen) in international development of transfusion medicine, involving all aspects of the management and operations of blood supply and clinical use systems at national level. Long-term member of WHO Expert Committee on Blood Transfusion. Fluent in Dutch, English, German. Conversant in French.
Prof Sibinga in full swing in the field.
Dutch nationality, Senior Partner of HEAP Research BV in project funding sourcing and banking. Jaap Wientjes is a professional on finance of projects in developing countries and emerging markets. He is a specialist in capacity building in the private sector and has extensive knowledge of international trade, export and investing in less developed countries. He is an expert on donor funding and an experienced banker in financing export transactions. Has held senior management functions such as Director of the Department of Investment Promotion (ORET and Capacity building programmes; fund manager) at FMO bank, Director of Export Finance at ING Barings Bank and Senior Account manager at NCM (now Atradius). In addition to his role with HEAP Research BV, Jaap is owner of the advisory company Finance for Projects (www.financeforprojects.nl). Among his clients are/have been many major capital goods and services industry companies in the Netherlands, World Bank, IFC, MIGA, PUM and government institutions of developing countries (mainly in Africa and central and Eastern Europe, Vietnam, China, approximately 30 countries) as well as the Minister of Economic Affairs in the Netherlands. Extensive network in the financial sector and more than 30 years of financing projects in developing countries. Jaap is expert in structuring and arranging finance solutions for projects on the basis of combinations of commercial and donor funding. Expert in developing ORIO proposals (more than 30 prepared, 70% of which successfully concluded) and PSI proposals, feasibility studies for investments in infrastructure and how to structure and arrange financing. In summary, Jaap is active in the overlapping field of government, policymakers and the private sector, in the Netherlands and even more so internationally. Fluent in Dutch and English, conversant in French and German.